Lac Van Tran, MD, CIO, and Julio C. Silva, MD, CMIO at Rush University Medical Center in Chicago, discuss the benefits of a strong partnership between the CIO and CMIO of a medical facility. They share how their collaboration has enabled more effective medical informatics education, technology implementation and integration in the clinical practice and the migration from a paper-based environment to an automated environment. The interview was conducted by William F. Bria, MD, Chief Medical Information Officer, Shriners Hospital for Children, and Chair of the HIMSS/AMDIS Physician Community.