In this episode, Dr. Jeremy Koenig sits down with Thomas Roos, a Stanford-trained genomicist, elite triathlete, and digital twin pioneer, to explore the cutting-edge intersection of genetics, sports science, and human performance. Roos shares his expertise in optimizing training, enhancing recovery, and reducing injury risk through genomic insights, highlighting his work with elite athletes, professional teams, and groundbreaking research in polygenic risk scoring. From discussing the role of continuous glucose monitoring and hydration strategies to the future of AI-driven genomics and precision health, this conversation unpacks the evolving landscape of performance-based medicine. Whether you're an athlete, coach, or someone looking to maximize your potential, this episode offers a deep dive into how DNA can unlock sustainable greatness. 

What You'll Learn:

• Genomics in Sports Performance – Understanding an athlete’s DNA can optimize training, enhance recovery, and reduce injury risks through personalized approaches.
• Polygenic Risk Scoring (PRS) – PRS helps assess genetic predispositions to injury, recovery speed, and athletic performance potential, allowing for tailored interventions.
• The Role of Continuous Glucose Monitoring (CGM) – Tracking glucose response in real-time helps athletes refine nutrition strategies to maintain energy levels and optimize endurance.
• Hydration & Electrolyte Balance – Athletes have unique sweat and sodium loss profiles, making individualized hydration crucial for maintaining peak performance.
• AI & Digital Twins in Human Performance – AI-driven genomics and digital twin modeling will enable more precise, data-driven decision-making for athlete training and recovery.
• The Importance of Recovery – Sleep, nutrition, and hydration play a vital role in reducing injury rates and ensuring sustainable peak performance.
• Personalized Training Over Generic Plans – Instead of a one-size-fits-all approach, genetic insights allow training regimens to be customized to an athlete’s unique biology.
• Future of Precision Medicine in Sports – The integration of omics, wearables, and AI in professional sports is paving the way for personalized, predictive, and practical health solutions.

Connect with Thomas

LINKS:

https://www.drjeremykoenig.com/
https://www.instagram.com/drjeremykoenig/
https://www.youtube.com/@drjeremykoenig

Here's the link for this week's episode: https://drjeremykoenig.substack.com/p/the-polygenic-tapestry