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In this episode of Petri Dish Perspectives, we break down the 340B Drug Pricing Program, a little-known but massively influential policy shaping how hospitals, pharmacies, and drug manufacturers operate today. Created under the Health Resources and Services Administration, 340B was designed to help safety-net providers stretch scarce resources and serve vulnerable patients.

But over time, it has evolved into something much bigger.

We unpack how the program actually works, why it’s become a financial cornerstone for many hospital systems, and the growing tension with pharmaceutical companies like Pfizer and Johnson & Johnson. From contract pharmacy battles to questions around transparency and patient benefit, the 340B ecosystem sits at the center of one of the most complex, and controversial, debates in healthcare economics.

Because 340B isn’t just about drug discounts.

It’s about who captures value in the healthcare system and who it’s really meant to serve.

🎧 Listen now, stay curious, and don’t forget to subscribe for new episodes every Thursday!

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