This month we are joined by Dr Vivek Narayan who is assistant Professor of medicine at the Abramson Cancer Center, University of Pennsylvania, who discusses What Limits the Efficacy of CAR-T Cell Therapies for Advanced Prostate Cancer. We also hear from our co-chair, Dr Sumit Subudhi, from MD Anderson Cancer Center, Texas, who will present on The Path Forward for Immune Checkpoint Therapies. Dr Subudhi also co-chairs the session and leads the disucssion to close the episode.