This talk goes over the most common causes of inhirted bleeding disorders.  There are two major types of hemophilia – deficiency in factor VIII and IX – which predominant occur in men.  Hemophilia A is deficiency of factor VIII and is the most common form of hemophilia treated with factor concentrate.  Hemophilia B is less common but treatment principles are the same.  There are multiple types of von Willebrand Disease as this is a complex molecular that both carries factor VIII and forms large multimers essential for platelet function.   Mild forms of vWD can be treated by desmopressin but von Willebrand factor is needed for more severe types.