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Episode 7 - Diabetes Remission, Sustainable Weight Loss, and Bariatric Surgery


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An overview on the hope that diabetes can go into remission with lifestyle changes. Sustainable weight loss, utilizing small but consistent adjustments that are realistic for the individual to maintain throughout their lives. The role of bariatric surgery in diabetes.

Sources used:

Lean, M. E. J., Leslie, W. S., Barnes, A. C., Brosnahan, N., Thom, G., McCombie, L., Peters, C., Zhyzhneuskaya, S., Al-Mrabeh, A., Hollingsworth, K. G., Rodrigues, A. M., Rehackova, L., Adamson, A. J., Sniehotta, F. F., Mathers, J. C., & Taylor, R. (2018). Primary care-led weight management for remission of type 2 diabetes (DiRECT): An open-label, cluster-randomised trial. The Lancet, 391(10120), 541-551. https://doi.org/10.1016/S0140-6736(17)33102-1

Look AHEAD Research Group. (2014). Eight-year weight losses with an intensive lifestyle intervention: The Look AHEAD study. Obesity, 22(1), 5-13. https://doi.org/10.1002/oby.20662

Mingrone, G., Panunzi, S., De Gaetano, A., Guidone, C., Iaconelli, A., Leccesi, L., Nanni, G., Pomp, A., Castagneto, M., & Ghirlanda, G. (2015). Bariatric surgery versus conventional medical therapy for type 2 diabetes. The New England Journal of Medicine, 365(4), 236-246. https://doi.org/10.1056/NEJMoa1200111

Sofi, F., Abbate, R., Gensini, G. F., & Casini, A. (2010). Accruing evidence on benefits of adherence to the Mediterranean diet on health: An updated systematic review and meta-analysis. The American Journal of Clinical Nutrition, 92(5), 1189-1196. https://doi.org/10.3945/ajcn.2010.29673

Schwingshackl, L., & Hoffmann, G. (2014). Long-term effects of low glycemic index/load vs. high glycemic index/load diets on parameters of obesity and obesity-associated risks: A systematic review and meta-analysis. Nutrition, Metabolism, and Cardiovascular Diseases, 24(8), 823-836. https://doi.org/10.1016/j.numecd.2014.03.005

Johns, D. J., Hartmann-Boyce, J., Jebb, S. A., & Aveyard, P. (2014). Diet or exercise interventions vs combined behavioral weight management programs: A systematic review and meta-analysis of direct comparisons. Journal of the Academy of Nutrition and Dietetics, 114(10), 1557

National Institute of Diabetes and Digestive and Kidney Diseases: Bariatric surgery procedures

https://www.niddk.nih.gov/health-information/weight-management/bariatric-surgery/procedures

American Society for Metabolic and Bariatric Surgery: Metabolic and Bariatric Surgery - https://asmbs.org/patients/metabolic-and-bariatric-surgery

Cleveland Clinic: Bariatric Surgery Options - https://my.clevelandclinic.org/health/treatments/16944-bariatric-surgery-options

The New England Journal of Medicine: Bariatric Surgery versus Intensive Medical Therapy for Diabetes - 5-Year Outcomes - https://www.nejm.org/doi/full/10.1056/nejmoa1200225

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There is more to itBy Easton