The BWC Global Forum: Biotech, Biosecurity & Beyond

Episode #7: Large Viruses as Gene Therapy Platforms


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Dr. Lauren Oldfield, Director of Synthetic Genomics, Replay

April 17, 2023

In this episode, we discuss efforts to develop large DNA viruses, such as herpesviruses, as vectors to deliver gene therapies, including advantages over other types of pathogen platforms. Notably, large viruses enable the delivery of larger genes for therapeutic purposes, and the characteristics of herpes simplex viruses (HSV) can allow gene therapies to be delivered over longer periods of time.

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The BWC Global Forum: Biotech, Biosecurity & BeyondBy Johns Hopkins Center for Health Security