RheumRounds

Episode 7 – Why Seronegative Doesn’t Mean Inactive “No antibodies? No inflammation? Think again.


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🎙️ Episode 7 – Why Seronegative Doesn’t Mean Inactive

“No antibodies? No inflammation? Think again.”


In this episode of RheumRounds, Dr. Aravind Palraj takes on a common clinical myth — that autoimmune diseases can be ruled out by negative antibodies.


🧠 In just 7 minutes, you’ll learn:


  • Why seronegative RA is still erosive and disabling
  • How HLA-B27-negative axial SpA can be missed — especially in women
  • When to suspect ANA-negative lupus, and what else to test



🎯 Seronegativity doesn’t mean disease inactivity.

Autoimmunity is more than just labs — it’s about listening to the patient’s story.


🎧 Host: Dr. Aravind Palraj

🎓 Senior Resident, Clinical Immunology & Rheumatology

📍 Madras Medical College, Chennai

📱 Follow on X: @Rheumat_Aravind

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RheumRoundsBy Aravind.palraj