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Adding Truvia and like artificial sweeteners that contain the sweet alcohol erythritol could bump up your risk of heart attack and stroke 3 to 4-fold. This from a Cleveland Clinic study of 2149 Americans and 833 Europeans analyzing the relationship of their erythritol blood levels and their incidence of cardiovascular disease.

Those with the highest erythritol levels compared with those having the lowest were on average at 3.5 times higher risk for cardiovascular events. Every micromole increase in circulating erythritol bumped up cardiovascular event risk between 16 and 21%. In an accompanying study, the investigators tied this increased risk to erythritol’s propensity to increase blood-clotting. They also found that consuming the sweetener in the average drink or snack increases its blood levels by a factor of 1,000 for hours.

The study isn’t perfect, but it is the tip of a nasty iceberg. Erythritol is not only found in Truvia but is also added to Splenda, Equal, and Monk Fruit In The Raw and other Stevia offerings as well as a slew of other products. For now, the smart approach is to know what’s in the artificial sweetener you’re using and limit your consumption of erythritol. This is especially true if you have other risk factors for cardiovascular disease such as obesity, high blood pressure, or diabetes.

https://www.nature.com/articles/s41591-023-02223-9

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