Onconews

Estudos WSG-TP-II e MAINTAIN avaliam eficácia da terapia endócrina em diferentes cenários e combinações


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Referências:  

  1. Gluz O, Nitz UA, Christgen M, et al. Efficacy of Endocrine Therapy Plus Trastuzumab and Pertuzumab vs
  2. De-escalated Chemotherapy in Patients with Hormone Receptor–Positive/ERBB2-Positive
    Early Breast Cancer: The Neoadjuvant WSG-TP-II Randomized Clinical
    Trial. JAMA Oncol. Published online May 11, 2023.
    doi:10.1001/jamaoncol.2023.0646 https://jamanetwork.com/journals/jamaoncology/article-abstract/2804892
  3. Kalinsky K, Accordino MK, Chiuzan C, Mundi PS, Sakach E, Sathe C, Ahn H, Trivedi MS, Novik
  4. Y, Tiersten A, Raptis G, Baer LN, Oh SY, Zelnak AB, Wisinski KB, Andreopoulou
    E, Gradishar WJ, Stringer-Reasor E, Reid SA, O'Dea A, O'Regan R, Crew KD,
    Hershman DL. Randomized Phase II Trial of Endocrine Therapy With or Without
    Ribociclib After Progression on Cyclin-Dependent Kinase 4/6 Inhibition in
    Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative
    Metastatic Breast Cancer: MAINTAIN Trial. J Clin Oncol. 2023 May 19:JCO2202392.
    doi: 10.1200/JCO.22.02392. Epub ahead of print. PMID: 37207300. https://ascopubs.org/doi/abs/10.1200/JCO.22.02392


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