I have heard so many stories about people who experience peace when they say no to hard things in life.  Let me tell you, it is ABSOLUTELY peaceful to not be doing meaningful things - especially the things that God has laid in front of us to do.

Its not your calling that burdens you, its your resistance to it that is causing you the pain.  Your calling will crush you, press you down and you will become refined and new in this process. Even when we can't feel it, God is working.