Dr. Thomas C. Detweiler, MD Podcast

Evolution and Clinical Impact of PDE5 Inhibitors


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In the intricate and occasionally humorous world of medical discoveries, phosphodiesterase type 5 (PDE5) inhibitors stand out as a particularly fortunate accident. Originally developed in the late 1980s for treating angina—a common heart condition characterized by chest pain—these compounds initially failed to significantly improve cardiac symptoms. 

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Dr. Thomas C. Detweiler, MD PodcastBy Dr. Thomas C. Detweiler