Recorded at the Consortium of Universities for Global Health annual meeting in Washington, D.C., this special bonus episode of Explore Global Health features Jarbas Barbosa da Silva Jr., MD, MPH, Ph, Director of the Pan American Health Organization (PAHO), in conversation with Rob Murphy, MD. The discussion explores what it takes to build resilient health systems in an increasingly complex global landscape, drawing on lessons from the COVID-19 pandemic, the evolving role of primary health care, and the importance of regional collaboration, governance, and trust. Barbosa also shares insights on the future of global health, including the growing role of artificial intelligence and advice for the next generation entering the field.