We unpack the OpenAI–Red Queen Bio study that had an AI design RAPF HiFi—RECA-assisted assembly paired with GP32, a novel temperature cycle, and a surprising downstream boost from pelleting cells at 4°C—that together delivered a 79x jump in cloning efficiency, validated by a robotic automation system. We break down the mechanism, the validation, and the implications for speeding biology from months to days, with a look at the future of AI-assisted wet labs.

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