Think you're stuck with an anxious, stressed brain? Think again. In this episode of The Cognitive Performer, Marco explores the neuroscience of fear extinction - your brain's natural ability to unlearn stress responses and build resilience instead. Discover why stress literally rewires your neural circuits, how fear conditioning keeps you stuck in anxiety loops, and the specific, science-backed techniques you can use to intentionally reshape your brain's stress response.

What You'll Learn:

• The difference between classical and operant conditioning (and why fear responses use the classical type)
• How chronic stress flattens your cortisol rhythm and damages neural connections
• Why your amygdala hijacks your prefrontal cortex during stress responses
• The three-step process of fear extinction and how it creates competing memories
• Why cyclic sighing outperforms mindfulness and box breathing for nervous system regulation
• How sleep actively rewires your brain through synaptic homeostasis
• Practical tools for building antifragility - getting stronger from stress instead of just surviving it

Key Topics:

Fear extinction, neuroplasticity, stress response, amygdala function, prefrontal cortex, cortisol regulation, classical conditioning, synaptic depression, parasympathetic activation, brain network connectivity, cognitive flexibility, antifragility

Practical Techniques Covered:

• 90-second cyclic sighing protocol for nervous system reset
• Mindfulness practices that break rumination loops
• Movement strategies for neuroplasticity and BDNF production
• Sleep optimization for emotional memory processing
• Building safe exposure routines for stress triggers

Perfect for: Voice actors, performers, creatives, anyone dealing with performance anxiety, stress management, or wanting to understand how to work with their brain instead of against it.

Research-Backed: All techniques discussed are supported by recent neuroscience studies from 2021-2025, with specific focus on fear extinction mechanisms, large-scale brain network changes, and evidence-based interventions for stress resilience.

Episode Length: 20 minutes

Connect: Have questions about brain rewiring or topics for future episodes? Email [email protected]

#NeurosciencePodcast #FearExtinction #StressManagement #Neuroplasticity #PerformanceAnxiety #BrainScience #VoiceActing #MentalPerformance #ResilienceTraining #CognitiveBehavioral

References

Fear Extinction

• Bergstrom, H. C., & Maren, S. (2024). Pharmacological stimulation of infralimbic cortex after fear conditioning facilitates subsequent fear extinction. Neuropsychopharmacology.
• Author(s). (2021). Rat models for low and high adaptive response to exercise differ for stress-related memory and anxiety. Physiological Reports.

Skill Learning & Mental Rehearsal

• Demaison, C., et al. (2022). Mental practice modulates functional connectivity between the cerebellum and the primary motor cortex. iScience.
• Xie, K., et al. (2022). Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons. Nature Neuroscience.

Mindfulness

• Brechmann, A., et al. (2022). Mindfulness meditation increases default mode, salience, and central executive network connectivity. Scientific Reports.
• Rogerson, A., et al. (2023). Mindfulness training changes brain dynamics during depressive rumination: A randomized controlled trial. Biological Psychiatry.
• Sousa, R., et al. (2024). Neurobiological changes induced by mindfulness and meditation: A systematic review. Brain Sciences.

Exercise & Stress

• Roth, M. M., et al. (2022). Learning and control in motor cortex across cell types and scales. Nature.
• Li, K., et al. (2021). Stress undermines reward-guided cognitive performance through synaptic depression in the lateral habenula. Neuron.

Sleep & Trauma

• Gvozdanovic, G. A., et al. (2023). Neural correlates of sleep-induced benefits on traumatic memory processing. Human Brain Mapping.
• van der Heijden, K. B., et al. (2022). Sleep spindle dynamics suggest over-consolidation in post-traumatic stress disorder. Sleep.
• Cairney, S. A., et al. (2024). Targeted memory reactivation to augment treatment in post-traumatic stress disorder. Current Biology.
• Schäfer, S. K., et al. (2023). The potential beneficial effect of sleep deprivation following traumatic events to preventing PTSD: Review of current insight regarding sleep, memory, and trauma resonating with ancient rituals. Neuropsychopharmacology Reports.

Copyright 2025 Marco Rigazio