In 1981, DEA Agent Enrique “Kiki” Camarena lands in Mexico. His task is to bring down the man known as El Padrino (The Godfather). This drug lord's real name is Miguel Ángel Félix Gallardo. Gallardo sits atop an industrial scale cocaine and marijuana operation, propped up by millions of dollars’ worth of bribes. He’s a man intertwined with the upper echelons of the Mexican establishment, a deadly spider at the centre of a web of corruption. Agent Camarena is only supposed to be stationed in Mexico for a few years. But his stint will end in horrific, unprecedented circumstances.

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