In this episode, we explore the complex pathophysiology of fibromyalgia, a chronic pain disorder impacting millions worldwide. From central sensitization and neurotransmitter imbalances to autonomic nervous system dysfunction, we discuss the science behind fibromyalgia’s persistent symptoms like widespread musculoskeletal pain, fatigue, and cognitive dysfunction, often called ‘Fibro Fog.’ Learn about key risk factors, diagnostic criteria, and both pharmacological and non-pharmacological treatment options, including exercise, sleep hygiene, and cognitive-behavioral therapy. This is a medical education podcast on the chronic pain condition fibromyalgia.