How have developments in research, drug development and management created new paradigms in the diagnosis and treatment of cancer and what this could mean for the future. Interviewees include: Dr Carlos Cordon-Cardo, a physician-scientist known widely for his research in experimental pathology and molecular oncology at the Icahn School of Medicine at Mount Sinai; Brian Dranka, Ph.D., Manager of Biology, Agilent Cell Analysis Division; Hans Christian Peterson, Director of Scientific Affairs at Dako, Agilent Pathology Solutions.