Pastor Van talks about creating financial margin in life by focusing on three key principles: giving generously, working diligently, and living simply. He emphasizes that financial struggles are prevalent today and highlights that Jesus spoke more about money than any other topic, stressing the importance of managing it wisely. By giving generously first, individuals can experience blessings and positive returns from their efforts. Ultimately, Pastor encourages the congregation to submit their finances to God through prayer and practice these principles to achieve financial freedom and peace.