Clare McAfee, a nutrition and health coach, has a taste for adventure and travel with a long bucket list. But in 2016, she was diagnosed with a condition called Interstitial Cystitis, or “IC”, a chronic condition causing bladder and pelvic pain—so terrible in her case that she compares it to living with shards of glass in her bladder all the time. She eventually discovered that a hormone imbalance was at the root of her condition. What has helped her find relief is using estrogen, adjusting diet, doing intensive pelvic floor physiotherapy, and using medical marijuana. She’s been able to manage IC so well that she’s now in remission — all this, after doctors told her she’d never find a cure.