Sign up to save your podcasts
Or
Share First FDA Approved Oral Drug For Postpartum Depression
Share to email
Share to Facebook
Share to X
Share to email
Share to Facebook
Share to X
Or
First FDA Approved Oral Drug For Postpartum Depression
Vidcast: https://www.instagram.com/p/Cy_f7hvRw2w/
One in every 8 new mothers experience postpartum depression. The number is surging with a 7-fold increase over a 15 year period. The FDA has now approved the oral neuronsteroid drug zuranolone, branded by Sage Therapeutics/Biogen as Zurzuvae. This drug is a synthetic version of the naturally occurring allopregnanolone that stimulates the brain’s GABA-A receptors leading to a calming and antidepressant effect. Phase 3 clinical trials have demonstrated that this oral drug works to effectively ease depression within 3 days whereas conventional therapy requires injections and may take weeks to become effective. The downside: the drug passes into breast milk precluding breast-feeding until studies show that zuranolone is safe for newborns.
https://www.fda.gov/news-events/press-announcements/fda-approves-first-oral-treatment-postpartum-depression
https://www.yalemedicine.org/news/postpartum-depression-pill-zurzuvae-zuranolone
https://www.cdc.gov/reproductivehealth/features/maternal-depression/index.html
#postpartum #depression #zuranolone #Zurzuvae #breastfeeding
View all episodes
By Howard G. Smith MD, AMVidcast: https://www.instagram.com/p/Cy_f7hvRw2w/
One in every 8 new mothers experience postpartum depression. The number is surging with a 7-fold increase over a 15 year period. The FDA has now approved the oral neuronsteroid drug zuranolone, branded by Sage Therapeutics/Biogen as Zurzuvae. This drug is a synthetic version of the naturally occurring allopregnanolone that stimulates the brain’s GABA-A receptors leading to a calming and antidepressant effect. Phase 3 clinical trials have demonstrated that this oral drug works to effectively ease depression within 3 days whereas conventional therapy requires injections and may take weeks to become effective. The downside: the drug passes into breast milk precluding breast-feeding until studies show that zuranolone is safe for newborns.
https://www.fda.gov/news-events/press-announcements/fda-approves-first-oral-treatment-postpartum-depression
https://www.yalemedicine.org/news/postpartum-depression-pill-zurzuvae-zuranolone
https://www.cdc.gov/reproductivehealth/features/maternal-depression/index.html
#postpartum #depression #zuranolone #Zurzuvae #breastfeeding