Tom Maniatis is a founder of Kallyope, and head of the Maniatis lab at Columbia University. Among other things, he's founded several biotechs and authored a manual nicknamed 'the bible of cloning.' His conversation with Nature Biotechnology covers being the first in his family to go to college, the moratorium on recombinant DNA research in Cambridge, Massachusetts, and his long relationship with Jim Watson at Cold Spring Harbor. For information regarding your data privacy, visit acast.com/privacy