Walter Isaacson has made a habit of profiling world-changers: innovators who, through their discoveries, upend the way we live. Recently, he’s been preoccupied with individuals who have unlocked what he calls “fundamental kernels of our existence” - first Albert Einstein and the atom, then Steve Jobs and the bit, and now, in his latest work, Jennifer Doudna and the gene.

In The Code Breaker, Isaacson dives into the CRISPR revolution and how the booming field of gene editing is altering how we treat disease and think about what it means to be human. Jennifer Doudna, who shared the 2020 Nobel Prize in Chemistry for her role in developing CRISPR, is Isaacson’s centerpiece as he guides readers through this new frontier, and the pressing moral questions that sophisticated, cutting-edge biological tools now pose.

** This episode has been reuploaded with the correct audio.