External Control Arms are a powerful clinical research tool, harnessing cutting-edge tech to fill gaps in clinical data and accelerate trials when patients’ lives are on the line. They’re particularly valuable for cancer research, where patients can neither afford to wait nor settle for the current standard of care.

Friends of Cancer Research President and CEO Jeff Allen sits down with Medidata CEO Anthony Costello and Senior Vice President, Statistics and Regulatory Science Innovation Ruthie Davi to celebrate 30 years of oncology innovation, and explore what’s coming next.

They dig deep into Medidata and Friends’ partnership to bring the power of External Control Arms to pancreatic cancer research, and how to build a future where clinical research takes full advantage of these life-saving innovations.

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NEXT New York is our flagship event, bringing together the world’s leading life sciences companies and thinkers to envision a transformative future for healthcare that challenges our preconceptions of what’s possible in clinical trials.

This special edition of from Dreamers to Disruptors was recorded live from the show floor at NEXT, capturing the hottest takes and insights from Medidata leaders and special guests. From the end-to-end AI support reshaping studies, to building trust in cutting-edge clinical technologies, our speakers share their fresh perspectives on what matters most to pharma professionals today.

Session 1 Speakers:

• Edward Ford | Vice President, Client Engagement, Medidata
• Anthony Costello | CEO, Medidata
• Matteo di Tommaso | Senior Vice President, R&D Business Insights & Technology, Bristol Myers Squibb
• Nimita Limaye | Research Vice President, Life Sciences R&D Strategy and Technology, IDC

Session 2 Speakers:

• Aryana Hosseinkhani | Vice President, Head of Product Marketing, Medidata
• Meghan Harrington | Vice President, Clinical Trial Financial Management, Medidata
• Paul O'Donohoe | Senior Director, eCOA Product and Science, Medidata
• Sharlene Carnegie | Senior Vice President, Product and Engineering, Medidata

Session 3 Speakers:

• Jeff Ventimiglia | Senior Vice President, Offering and Portfolio Management, Medidata
• Bryant Fields | Vice President, Partnerships, Medidata
• Robert Lyons | Vice President, Engineering, Medidata
• Jia Chen | Head, Product, AI, Medidata

Session 4 Speakers:

• Lisa Moneymaker | Senior Vice President, Chief Strategy Officer, Medidata
• Tom Doyle | Senior Vice President, Chief Technology Officer, Medidata
• Claire Biot | Vice President, Life Sciences and Healthcare Industry, Dassault Systèmes
• Patrick Johnson | EVP, Corporate Research and Sciences, Dassault Systèmes

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As a veteran entrepreneur in life sciences, Lee Shapiro has invested in some of the most transformative technologies in modern healthcare history—developing a deep understanding of what makes for truly successful innovation.

Medidata CEO Anthony Costello sits down with Lee to discover the secret to his success. Charting his work across a variety of leading life sciences organizations, from Allscripts and Livongo, to Click Therapeutics and Medidata itself, Lee uncovers the qualities that underpin the most accomplished enterprises.

Join Lee and Anthony as they paint a powerful picture of our evolving industry and explore the disruptions shaping the future of healthcare.

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As we enter the new year, the mandate is clear: evolve clinical research or get left behind.

Join us to revisit conversations between Medidata CEO Anthony Costello and some of the leading industry minds—including Every Cure’s David Fajgenbaum, Digital Medicine Society’s Jennifer Goldsack, and Click Therapeutics’ David Klein—as they look to the future of life sciences in 2026 and beyond.

From unlocking deeper data insights to scaling radical innovation, our guests issue a direct call to action: harness today’s cutting-edge technology to build a faster, smarter, and healthier world for patients everywhere.

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David Fajgenbaum’s relationship to drug repurposing is personal, professional, and one of the most inspiring stories in modern medicine. Diagnosed with Castleman disease and running out of treatment options, David used his research skills to identify an existing drug that saved his life.

Join David and Medidata CEO Anthony Costello to explore the origins of Every Cure—and how David’s experience became the seed for a nonprofit that uncovers life-changing uses for treatments already approved for other conditions. Discover Every Cure’s innovative approaches to data, the scope of unmet needs across healthcare, and how pharmaceutical companies can contribute to a future where we unlock the full potential of treatments for all.

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Jennifer Goldsack has made it her mission to push the boundaries of how technology can enhance healthcare. As founder and CEO of the Digital Medicine Society (DiMe), she supports digital innovators exploring new ways to deliver better outcomes for patients everywhere.

Jennifer and Medidata CEO Anthony Costello explore how clinical trials once led the way in life sciences digitization, why they’re falling behind, and how we can get our industry back on track.

Join them to discover how Jennifer is promoting innovation and making smarter use of clinical data, as well as her personal story of navigating the healthcare system and confronting the everyday challenges patients face.

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Patient-centric trials are essential for the future of clinical development, but there are hurdles to overcome. The industry must adapt to the needs and preferences of patients, incorporate high-quality data, and embrace innovative technology so patients and trials can thrive together.

IQVIA is leading the healthcare industry with its unparalleled management of clinical data. SVP, Data Sciences, Safety and Medical Writing Tracy Mayer sits down with Medidata CEO Anthony Costello to explore the growth of patient-centric trials and the adoption of AI that have made this growth possible.

Join Tracy and Anthony to discover the future of data management and how it will improve data acquisition and accelerate data delivery, ultimately easing the stress of patient journeys.

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Digital therapeutics are poised to transform healthcare as we know it, delivering Software-Enhanced Drugs™ to patients that extend and expand on traditional treatments, as well as valuable data and new commercial opportunities to pharmaceutical companies.

Click Therapeutics is a leading light in prescription digital therapeutics, and CEO David Benshoof Klein’s insights into their design and implementation are second to none. He joins Medidata Solutions’ CEO Anthony Costello to explore the growth of evidence-based, Software-Enhanced Drugs™ and the art of creating effective technologies that change lives.

Join David and Anthony to explore the vast potential of digital therapeutics for treating everything from migraines to cancer, and how to build solutions that genuinely benefit patients. They discuss the new Regulatory Considerations for Prescription Drug Use-Related Software (PDURS), and what new legislation means for the growth of software-based treatment adoption around the world.

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When it comes to understanding the application and potential of AI in clinical trials, you’re unlikely to find a greater expert than Arnaub Chatterjee, Datavant’s GM and president, life sciences, ecosystem and public sector.

Arnaub has experience working for private companies, the US government, and as a teacher at Harvard Medical School, giving him unparalleled insight into the AI technologies reshaping study design and helping us to draw valuable insights from the vast amounts of data captured by healthcare organizations.

Join Arnaub and Medidata CEO Anthony Costello as they take a deep dive into the cutting-edge of clinical data management. They explore Arnaub’s pioneering work in the early days of Medidata’s adoption of AI, how we can ensure that our models are reliable and unbiased, and our collective project to build an environment that leverages patient data between and beyond clinical trials.

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Marisa Co has built a career based on intimate knowledge of every aspect of the pharmaceutical industry, giving her unparalleled insight into clinical trials and how to drive change in life sciences. Alongside senior roles at some of the biggest names in healthcare, her participation in the launch of Mytrus paved the way for decentralized clinical trials (DCTs).

Join Marisa and Medidata CEO Anthony Costello as they dive into the technologies that enable DCTs to give patients ownership of their clinical trial journeys, and the AI boom that is transforming every aspect of clinical research.

Marisa shares her unique insights into overcoming risk aversion within the clinical trials industry, and ensuring the successful adoption of game-changing technologies. She and Anthony dig into the progress of incorporating AI and eConsent into studies, and how to successfully deliver transformative change in healthcare.

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