The Great Commission in Matthew 28:16-20 represents Jesus' final instructions to make disciples of all nations. True discipleship involves loving God, growing in Christlikeness, serving others, and sharing the gospel. To fulfill this mission, believers must be available by creating margin in their schedules, worshipful in lifestyle, submissive to Christ's authority, obedient to His commands, and dependent on His presence. This isn't just about church attendance but about transformation and reproduction—helping others experience new life in Christ and then equipping them to disciple others.