This episode examines the evolving landscape of intracranial EEG techniques for epilepsy presurgical evaluation, drawing on data from "Transition from Subdural Electrocorticography to Stereo-electroencephalography in Presurgical Evaluation of Epilepsy: Single-institutional Experience," published in Neurologia medico-chirurgica in 2026. Based on an abstract of a retrospective review of 83 patients, this discussion compares stereo-electroencephalography (SEEG) with subdural electrode implantation (SEEG) in terms of target regions, complications, and surgical outcomes. Key findings suggest comparable seizure freedom rates but a notable reduction in serious complications and increased utility of SEEG in complex cases, particularly when involving deep brain structures. This episode is for informational purposes and does not constitute medical advice. This content is AI-generated and should be critically reviewed by medical professionals.