PodBites

Gastroenterology | Constipation & Laxatives

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🍐 In this episode of PodBites, Habiba Othman and Hayaa Elsherif guide you through constipation — from diagnostic criteria to laxative pharmacology — using clinical reasoning, physiologic mechanisms, and high-yield treatment principles.

🎙️ Tune in to explore:

  • The clinical definition of constipation and the Rome IV diagnostic criteria
  • The Bristol Stool Chart and how stool form reflects transit time
  • The physiology of defecation and the role of autonomic innervation and interstitial cells of Cajal
  • Functional, structural, neurologic, metabolic, and medication-induced causes of constipation
  • The stepwise diagnostic approach, including alarm features and specialized testing
  • First-line management with lifestyle modification and when pharmacologic therapy is needed
  • Laxative classes, including bulk, stimulant, osmotic, stool softeners, and lubricants
  • Special agents like lactulose and lubiprostone and their clinical indications

    • 🌟 A structured, high-yield guide to understanding constipation, helping you connect physiology, diagnosis, and treatment with confidence.§

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    PodBitesBy palbites2023