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February 14, 2026

Gastroenterology | Diarrhea & Anti-Diarrheals

18 minutes

🍐 In this episode of PodBites, Nour and Tala guide you through diarrhea — from pathophysiology to pharmacologic management — using clinical reasoning, diagnostic frameworks, and high-yield treatment principles.

🎙️ Tune in to explore:

The clinical definition of diarrhea and how duration shapes the differential

The four major mechanisms: secretory, osmotic, inflammatory, and motility-related diarrhea

How to distinguish small bowel from large bowel diarrhea using clinical clues

Infectious causes and how incubation period helps identify the pathogen

The diagnostic approach to acute versus chronic diarrhea, including osmotic gap interpretation

Oral rehydration, fluid assessment, and essential management priorities

Antidiarrheal drugs, including loperamide, diphenoxylate, bismuth, and their mechanisms

Octreotide and its role in treating severe secretory diarrhea

🌟 A structured, high-yield guide to understanding diarrhea, helping you connect physiology, diagnosis, and treatment with confidence.

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By palbites2023