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Gastrointestinal - Peptic Ulcer Disease
In this episode, we review peptic ulcer disease (PUD) with a practical, clinically focused approach. We cover underlying pathophysiology, key risk factors—including H. pylori and NSAID use—classic symptoms, and important complications such as bleeding and perforation. The discussion highlights diagnostic strategies, evidence-based treatment, and prevention pearls to help clinicians confidently evaluate and manage patients with upper GI complaints.
References
1) Bushardt RL, Colomb-Lippa DM, Klinger AM, Reed H. The JAAPA QRS Review for PAs: Study Plan and Guide for PANCE and PANRE. 1st ed. LWW; 2021. ISBN: 9781975143817.
2) American College of Gastroenterology. Peptic ulcer disease (PUD). GI.org. https://gi.org/topics/peptic-ulcer-disease/. Accessed January 22, 2026.
3) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Peptic ulcers (stomach ulcers) — definition & facts. NIDDK.nih.gov. https://www.niddk.nih.gov/health-information/digestive-diseases/peptic-ulcers-stomach-ulcers/definition-facts. Accessed January 22, 2026.
4) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Peptic ulcers (stomach ulcers). NIDDK.nih.gov. https://www.niddk.nih.gov/health-information/digestive-diseases/peptic-ulcers-stomach-ulcers. Accessed January 22, 2026.
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By Kristopher Maday, PA-C, DFAAPAIn this episode, we review peptic ulcer disease (PUD) with a practical, clinically focused approach. We cover underlying pathophysiology, key risk factors—including H. pylori and NSAID use—classic symptoms, and important complications such as bleeding and perforation. The discussion highlights diagnostic strategies, evidence-based treatment, and prevention pearls to help clinicians confidently evaluate and manage patients with upper GI complaints.
References
1) Bushardt RL, Colomb-Lippa DM, Klinger AM, Reed H. The JAAPA QRS Review for PAs: Study Plan and Guide for PANCE and PANRE. 1st ed. LWW; 2021. ISBN: 9781975143817.
2) American College of Gastroenterology. Peptic ulcer disease (PUD). GI.org. https://gi.org/topics/peptic-ulcer-disease/. Accessed January 22, 2026.
3) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Peptic ulcers (stomach ulcers) — definition & facts. NIDDK.nih.gov. https://www.niddk.nih.gov/health-information/digestive-diseases/peptic-ulcers-stomach-ulcers/definition-facts. Accessed January 22, 2026.
4) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Peptic ulcers (stomach ulcers). NIDDK.nih.gov. https://www.niddk.nih.gov/health-information/digestive-diseases/peptic-ulcers-stomach-ulcers. Accessed January 22, 2026.