The Biorevolution Podcast

Gene drives - Menschengemachte Evolution


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The biorevolution podcast #4

GERMAN EPISODE

Sogenannte Gene Drives sind spezielle Genveränderungsmethoden, die es Wissenschaftlern zum ersten Mal erlauben die Grenzen der klassischen Evolution nach Darwin zu sprengen und ihr Grundprinzip, die natürliche Selektion zu überwinden, in dem sie die Expression in allen Nachkommen erzwingen. In dieser Episode unterhalten sich Andreas Horchler und Louise von Stechow darüber wie Gene Drives in der Malariaprävention, in der Bewahrung bedrohter Arten und zur Erhöhung von Ernteerträgen eingesetzt werden könnten – und wie gefährlich diese Technologie in der Hand eines einzelnen Wissenschaftlers sein kann.

Content and Editing:

Louise von Stechow and Andreas Horchler

Disclaimer:

Louise von Stechow, Andreas Horchler and their guests express their personal opinions, which are founded on research on the respective topics, but do not claim to give medical, investment or even life advice in the podcast.

Learn more about the future of biotech in our podcasts and keynotes. Contact us here:

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Keynotes: https://www.zukunftsinstitut.de/louise-von-stechow

Image:

Ryan Grybill Via Unsplash

References

1) https://www.nature.com/articles/d41586-019-02087-5
2) https://pubmed.ncbi.nlm.nih.gov/21508956/
3) https://www.who.int/teams/global-malaria-programme/reports/world-malaria-report-2021
4) https://www.statnews.com/2017/03/14/malaria-mosquitoes-burkina-faso/
5) https://www.statnews.com/2016/12/14/gene-drive-students-igem/
6) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675690/
7) https://www.statnews.com/2015/12/07/gene-edited-mosquitoes-stop-malaria/
8) https://psmag.com/ideas/most-controversial-tree-in-the-world-gmo-genetic-engineering
9) https://theconversation.com/genetically-modified-mosquitoes-could-be-released-in-florida-and-texas-beginning-this-summer-silver-bullet-or-jumping-the-gun-139710
10) https://www.editingnature.org/
11) https://www.statnews.com/2015/11/12/gene-drive-bioterror-risk/#:~:text=The%20possibilities%20for%20%E2%80%9Cweaponizing%E2%80%9D%20gene,who%20briefed%20the%20bioweapons%20office.
12) https://www.ajtmh.org/view/journals/tpmd/96/3/article-p530.xml
13) https://elifesciences.org/articles/03401
14) https://www.pnas.org/doi/10.1073/pnas.1805874115
15) https://www.etcgroup.org/content/reckless-driving-gene-drives-and-end-nature
16) https://www.vice.com/en/article/kz49ge/this-gene-technology-could-change-the-world-its-maker-isnt-sure-it-should-v26n4
17) https://medium.com/mit-media-lab/daisy-drives-will-let-communities-alter-wild-organisms-in-local-ecosystems-cb626c5a9f38#.91i6eyhc0

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The Biorevolution PodcastBy Louise von Stechow