This series of case presentations branches out from the usual idiopathic Group 1 patient types and explores more unusual and challenging cases. The series looks at adult congenital heart disease-associated PH, uncommon PH associated with non-scleroderma connective disease, combined pre-and post-capillary PH and other patient types. Viewers will gain insights into the identification, diagnosis and treatment options available for each of the unusual cases included in the series.