The central message of this sermon is that the pursuit of pleasure and happiness is a fundamental human desire that is good in itself, rather than inherently selfish or wrong. This desire should drive us to seek God, rather than being misguided towards created things. The sermon suggests that we often misunderstand what it means to seek God's pleasure, thinking that self-denial and unselfishness are the primary virtues, when in fact they can be a negative and unhelpful approach. Instead, the Bible teaches that our desires should be directed towards God, and that He finds our desires too weak, not too strong. The sermon encourages listeners to pursue their desire for happiness and pleasure in relation to God, rather than trying to suppress or go without them. This advances the belief that human beings are created to seek relationship with God, and that this is a fundamental aspect of the Christian faith.