The sermon explores the pervasive wickedness of humanity, as depicted in Genesis 6, and examines how God, despite this pervasive sin, extends grace, exemplified by Noah's favor. It highlights the doctrine of total depravity, emphasizing that human thoughts and intentions are inherently evil, yet God's loving-kindness and covenant faithfulness remain constant. Ultimately, the message underscores the importance of holding fast to God's sovereignty, character, and the gift of grace, finding comfort and assurance in Christ's sacrifice and the promise of redemption from sin and judgment.