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Why do promising discoveries sometimes get stuck between the lab bench and the real world? In this episode of Grow Everything, hosts Erum Azeez Khan and Karl Schmieder speak with Transfer AI cofounders Anne Marie Wagner and Renee Wegrzyn about the hidden steps that make scientific experiments difficult to reproduce and transfer. Drawing on their experience at Ginkgo Bioworks, DARPA and the Advanced Research Projects Agency for Health, they explain how cameras, environmental sensors and AI can capture the practical knowledge scientists rarely write down, helping teams understand which variations matter. The conversation explores reproducibility, technology transfer, investment risk, scientific creativity and a future where better data helps researchers bring discoveries to patients and the bioeconomy.
Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?
Learn more at www.messaginglab.com/groweverything
Chapters:
Links and Resources:
Topics Covered:
physical AI for science, AI in biology labs, lab reproducibility, scientific knowledge transfer, biotech tech transfer, lab automation, experimental protocol optimization, AI-powered lab monitoring, biomanufacturing scale-up, scientific data capture
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Music by: Nihilore
Production by: Amplafy Media
What does it take to turn industrial carbon dioxide into useful chemicals at a price the market will accept? On Grow Everything, Karl Schmieder and Erum Azeez Khan speak with Max Kufner, cofounder and CEO of Again, about using gas fermentation to make acetate and other products from industrial emissions. Max explains why feedstock economics and locating production close to customers matter, what the acquisition of Genomatica brings to Again, and why real production data is essential for predicting whether a bioprocess can work at industrial scale. He also shares how customer demand, licensing, project finance, and partnerships can help move biotechnology from the lab into the real world. Before the interview, the hosts explore an AI assisted biomanufacturing class and the latest discussion around deextinction.
Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?
Learn more at www.messaginglab.com/groweverything
Chapters:
Links and Resources:
Topics Covered:
biomanufacturing, AI x bio, climate tech, green chemicals, sustainable manufacturing, industrial biotechnology, biotech scale-up, deep tech financing, carbon-negative products, alternative chemicals
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Music by: Nihilore
Production by: Amplafy Media
Michael Wright, founder of Biomimetics International, joins Grow Everything to explain how learning from nature can reshape the way we design products, build businesses, and scale emerging industries. Drawing on decades in semiconductors and high technology, he describes biomimetics as learning from nature’s tested systems, from burr inspired Velcro to shark skin that reduces drag, while emphasizing that copying a biological function is not enough if a product cannot return safely to the biosphere. He introduces the Biosverse, nature’s third number, and generational cost of ownership as ways to account for environmental liabilities that traditional business models may overlook. The conversation explores how digital and biological systems converge, why biotech can learn from semiconductor standards and roadmaps, how AI might benefit from a more nurturing and accountable design approach, and why leaders should ask, “Do you know what you do does?” Michael’s vision is a mindset shift that brings nature into the design process before we build, then measures whether innovations can serve communities and remain compatible with the living world.
Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?
Learn more at www.messaginglab.com/groweverything
Chapters:
Episode Links:
Topics Covered:
biomimetics, bio-inspired design, biosphere compatibility, generational cost of ownership, nature-inspired materials, biomimicry in engineering, sustainable data centers, AI and biomimicry, biomimetics industry standards, circular materials
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Music by: Nihilore
Production by: Amplafy Media
At Bio Innovations in Omaha and an adjacent investor gathering in Houston, Grow Everything hosts Karl Schmieder and Erum Azeez Khan unpack the shift reshaping the bioeconomy: scientific discovery is becoming faster and less expensive, while deployment, scale up, and durable partnerships have become the real competitive advantage. They share conversations from the conference floor on the missing middle between bench science and commercial production, the Midwest’s feedstock and infrastructure advantage, the need for early technoeconomic discipline, and how corporates can give innovators clearer demand and specification targets. From pilot facilities and downstream processing to waste to value opportunities and resilient domestic supply chains, this recap maps the practical work required to turn biological innovation into products that matter.
Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?
Learn more at www.messaginglab.com/groweverything
Chapters:
Links and Resources:
Topics Covered:
autonomous labs, laboratory robotics, AI in biotechnology, synthetic biology, bioengineering, biological automation, data as a service, biotech infrastructure, cell engineering, programmable biology
Have a question or comment? Message us here:
Text or Call (804) 505-5553
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Music by: Nihilore
Production by: Amplafy Media
Genoa Ventures founder and managing director Jenny Rooke joins Karl Schmieder and Erum Azeez to explore bioconvergence, the expanding frontier where biology meets AI, automation, materials science, and real world business building. Drawing on her journey from physics and genetics to venture capital, Jenny explains why durable bio based companies must pair novel science with clear customer demand, disciplined scale up, and a path to meaningful commercial value. The conversation examines lessons from early synthetic biology, the realities of biomanufacturing at scale, next generation clinical assessment tools, and why founders working between traditional tech and biotech categories need investors who understand both.
Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?
Learn more at www.messaginglab.com/groweverything
Chapters:
Links and Resources:
Topics Covered:
bioconvergence, deep tech venture capital, synthetic biology investing, biomanufacturing, life science tools, clinical diagnostics, industrial biotech, bioeconomy
Have a question or comment? Message us here:
Text or Call (804) 505-5553
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Music by: Nihilore
Production by: Amplafy Media
Michael Heltzen, CEO of Exozymes, joins Grow Everything to explain how cell free biomanufacturing is opening new possibilities for natural products, nutraceuticals, and medicines. Michael shares why engineered enzymes can make high purity molecules without relying on living cells, how Exozymes moved its NCT program from discovery toward commercial manufacturing in less than two years, and why its capital light partnership model is central to scaling impact. The conversation also explores AI guided enzyme design, digital twins for manufacturing, rare cannabinoids, downstream processing, and the disciplined focus required to turn a broad biotechnology platform into real products.
Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?
Learn more at www.messaginglab.com/groweverything
Chapters:
Links and Resources:
Topics Covered:
cell-free biomanufacturing, enzyme engineering, exozymes, biosynthesis, cannabinoids, NCT (N-trans-caffeoyltyramine), synthetic biology, AI-driven enzyme design, scalable bioproduction, sustainable chemicals
Have a question or comment? Message us here:
Text or Call (804) 505-5553
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Music by: Nihilore
Production by: Amplafy Media
For the 200th episode of Grow Everything, Karl Schmieder and Erum Azeez Khan talk with Jason Kelly, co-founder and CEO of Ginkgo Bioworks and former chair of the US National Security Commission on Emerging Biotechnology, about why biology is still so hard to engineer. Jason explains why a cell is the only coded substrate we have besides a computer, why the real bottleneck is tooling rather than ideas, and why Ginkgo moved from royalty based research partnerships to selling robotic hardware and lab data as a service. Using a subway, car and Waymo analogy, he separates automation from autonomy and makes the case for replacing the manual lab bench, which eats roughly 97 percent of research spending while running 40 hours out of 168. He walks through Ginkgo's Boston system of 105 robots running 24/7, new autonomous labs for MIT, Caltech, Northwestern and the University of Maryland, and the OpenAI project where GPT-5 ran 30,000 experiments a week and beat state of the art in cell free protein synthesis by 40 percent. He also lays out the policy stakes as drug discovery shifts to China, and why the day biology becomes predictably easier to engineer, biotech gets bigger than tech.
Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?
Learn more at www.messaginglab.com/groweverything
Chapters:
Links and Resources:
Topics Covered:
autonomous labs, laboratory robotics, AI in biotechnology, synthetic biology, bioengineering, biological automation, data as a service, biotech infrastructure, cell engineering, programmable biology
Have a question or comment? Message us here:
Text or Call (804) 505-5553
Instagram / Twitter / LinkedIn / Youtube / Grow Everything
Music by: Nihilore
Production by: Amplafy Media
Biology may be the most important technology we take off planet, and Mario Maggio is building the hardware to prove it. The founder and CEO of Ambrosia Space joins Erum Azeez Khan and Karl Schmieder to explain why space bioprocessing has been stuck at 10 to 20 milliliters while bench scientists on Earth work at 250 milliliters and beyond, and what changes when a two and a half liter fed batch bioreactor with pH, dissolved oxygen, and total cell density sensors finally flies. Mario traces his path from aerospace propulsion and the Nova C lunar lander at Intuitive Machines to life support systems at Paragon and Axiom Space, and the realization that biology is the best CO2 scrubber, oxygen source, and chemical factory available for long duration missions where petroleum, farms, and easy resupply do not exist. The conversation digs into the engineering reality of fluids and gas in microgravity, why glass and ceramics never fly, the stainless steel and aluminum builds that replace them, the intentional and unintentional bacteria that come with building a bioreactor from scratch, and the NASA TechLeap winning CellSep continuous flow centrifuge that carries cells and secreted products into downstream processing without gravity. Mario also lays out the near term commercial case, from protein crystallization and monoclonal antibodies that behave differently in orbit to biofuels, vitamin production, medicines, and the big silver tanks that will feed astronauts because there will be no farms or cattle. He offers a candid read on artificial gravity gradients, why the Moon matters for building large vehicles in space, and why the same hardware that grows yeast for beer on Mars becomes the root of better biomanufacturing on Earth. Erum and Karl open with field notes from Bio Innovations North America in Omaha, including Midwest feedstock advantage, consortia momentum, the 30 percent of cost hiding in downstream processing, and why Smucker and Mars are actively scouting biotech innovators.
Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?
Learn more at www.messaginglab.com/groweverything
Chapters:
Links and Resources:
Topics Covered:
space biomanufacturing, Ambrosia Space, orbital bioreactors, microgravity biotechnology
Have a question or comment? Message us here:
Text or Call (804) 505-5553
Instagram / Twitter / LinkedIn / Youtube / Grow Everything
Music by: Nihilore
Production by: Amplafy Media
Chef and entrepreneur Pierre Thiam joins Grow Everything to explain how fonio, a resilient ancient grain from West Africa, can become a platform for biodiversity, regenerative agriculture, food security, and farmer prosperity. Pierre traces his journey from studying physics and chemistry to discovering the kitchen as a larger system connecting culture, health, ecology, and economics. He shares why fonio is nutritionally dense, gluten free, drought resistant, fast cooking, and versatile, as well as how Yolélé is building aggregation centers and modern processing infrastructure while keeping cultivation knowledge and ownership with smallholder farming communities. The conversation explores how biotechnology can complement biodiversity, why flavor must lead climate friendly food adoption, how underutilized crops can create clean label ingredients and new commercial markets, and why food can serve as a powerful tool for diplomacy and cultural understanding. For founders, scientists, investors, and builders in the bioeconomy, Pierre offers a human centered model of innovation that begins with nature, respects generational knowledge, and uses technology to unlock solutions that have been in front of us all along.
Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?
Learn more at www.messaginglab.com/groweverything
Chapters:
Links and Resources:
Topics Covered:
Fonio, West African cuisine, sustainable food systems, regenerative agriculture, food biodiversity, underutilized crops, food diplomacy, Bambara groundnuts, climate-resilient crops, Yolélé
Have a question or comment? Message us here:
Text or Call (804) 505-5553
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Music by: Nihilore
Production by: Amplafy Media
Food technology is moving from farms and petrochemicals into bioreactors, fungi, engineered crops, and circular feedstocks. In this Grow Everything highlights episode, Erum Azeez and Karl Schmieder visit six stops across the grocery store to explore sweet proteins from Oobli, fermentation derived colorants from MycoFutures and Chromologics, the antioxidant rich purple tomato from Norfolk Healthy Produce, fungi based proteins from The Better Meat Co. and MyForest Foods, sargassum derived ingredients from Origin by Ocean, and the hard commercial work of getting emerging products onto retail shelves. For founders, scientists, investors, and builders across synthetic biology and sustainable materials, the central lesson is clear: fermentation is manufacturing, environmental problems can become valuable feedstocks, and biology wins when performance, taste, branding, and price are better for the customer.
Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?
Learn more at www.messaginglab.com/groweverything
Chapters:
Links and Resources:
Topics Covered:
Food technology is moving from farms and petrochemicals into bioreactors, fungi, engineered crops, and circular feedstocks. In this Grow Everything highlights episode
Have a question or comment? Message us here:
Text or Call (804) 505-5553
Instagram / Twitter / LinkedIn / Youtube / Grow Everything
Music by: Nihilore
Production by: Amplafy Media
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