Here is my summary of the AAOS (American Academy of Orthopedic Surgeons) Clinical Practice Guidelines on Management of Osteoarthritis of the Knee (Non-Arthroplasty) 3rd

1. Not Recommended
a. narcotic medication
b. viscosupplements (hyaluronic acid)
c. arthroscopic washout
d. orthotics
e. interposistional devices

2. Should Help
a. oral or topical Nsaids
b. acetaminophen
c. patient education
d. self management / supervised exercise

3. May Help
a. cane
b. brace
c. oral supplements (tumeric, ginger, glucosamine, chondrotin, vit D)
d. weight loss
e. neuromuscular training, manual therapy, massage
f. cortisone injections
g. PRP injections
h. denervation
i. menisectomy if other conservative options have failed
j. osteotomy

you can read the full guidelines here:

https://www.aaos.org/quality/quality-programs/lower-extremity-programs/osteoarthritis-of-the-knee/

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