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Finasteride and Its Effect on PSA Levels: A Simple Explanation


**Finasteride and Its Effect on PSA Levels: A Simple Explanation**


Let's dive into understanding a medicine called finasteride. It's like a superhero in the medical world, fighting against problems like an enlarged prostate (known as benign prostatic hyperplasia, BPH) and hair loss in men. What finasteride does best is blocking a hormone called dihydrotestosterone (DHT), which is responsible for making the prostate bigger.


When doctors want to check for prostate cancer, they look at something called PSA (prostate-specific antigen) levels. But here’s the catch - finasteride can change PSA levels, making them lower. Let's break down how it does this:


### **Making the Prostate Smaller:**

- **Tackling DHT:** Finasteride helps reduce DHT in the body. Less DHT means a smaller prostate, and a smaller prostate leads to lower PSA levels.

- **Connecting with PSA:** Using finasteride means that PSA levels could drop by about half within six months to a year.


### **Handling PSA Readings:**

- **Fine-tuning the Results:** Doctors, knowing what finasteride does, adjust the PSA readings a bit. They might double the value to get a clearer picture while keeping in mind the effect of finasteride.

- **Keeping the Screening Right:** These changes make sure that the PSA levels are accurate and helpful when checking for prostate cancer.


### **Understanding Cancer Detection Better:**

- **Maintaining Screening Quality:** Adjusting the PSA readings helps to keep the screening for prostate cancer effective and sensitive.

- **Thinking About Biopsy:** The new PSA levels help doctors decide whether a biopsy (taking a small tissue sample) of the prostate is necessary to look more closely for signs of cancer.


So, in simple words, finasteride is a helpful medication that brings changes in hormones and PSA levels. Understanding these changes and adjustments is key to getting the right picture of a person's prostate health.

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Recharge PodcastBy Mitchel Schwindt, M.D. | author | online courses | coaching | consulting

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