PodBites

Hematology | Hemolytic Anemias

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🍐 In this true-crime–themed episode of PodBites, Abdulrahman Aldahash and Amro Badra transform hemolytic anemias into a detective story — chasing down the culprits behind the premature “murder” of red blood cells.

🎙️ Tune in to learn about:

  • Intrinsic vs. extrinsic hemolysis — the “inside job” vs. the “outside assault”
  • Classic lab clues: ↑ indirect bilirubin, ↑ LDH, ↓ haptoglobin, ↑ reticulocytes
  • Extravascular vs. intravascular hemolysis
  • Hereditary Spherocytosis & Elliptocytosis — membrane defects, spherocytes, MCHC rise, diagnostic tests
  • G6PD Deficiency — oxidative stress, Heinz bodies, bite cells, triggers & timing of testing
  • Warm & Cold Autoimmune Hemolytic Anemia — IgG vs. IgM, DAT interpretation, treatment differences
  • TTP & HUS — schistocytes, microangiopathic clues, ADAMTS13, Shiga toxin, kidney vs. brain involvement
  • Paroxysmal Nocturnal Hemoglobinuria (PNH) — PIGA mutation, complement sensitivity, dark urine at night, eculizumab
  • High-yield comparisons, memory tricks, and case-based reasoning throughout

    • 🔍 A cinematic, high-yield exploration of every major cause of hemolytic anemia — taught through mystery, humor, and detective-style logic that makes the content unforgettable.

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    PodBitesBy palbites2023