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November 24, 2025

Hematology | Leukopenia & Leukocytosis

13 minutes

🍐 In this episode of PodBites, Cristella and Reham guide you through one of the most essential topics in clinical medicine — how to understand, interpret, and reason through leucocytosis and leucopenia.

🎙️ Tune in to learn about:

WBC lineages & morphology — neutrophils, eosinophils, basophils, lymphocytes, monocytes

WBC pools in the bone marrow & circulation

Mechanisms behind leucocytosis: increased production, release, demargination & decreased tissue migration

When high WBC counts are reactive vs. malignant

Neutrophilia, leukemoid reactions & LAP score interpretation

Eosinophilia (NAACP), basophilia, lymphocytosis & monocytosis

Infectious mononucleosis & atypical lymphocytes

Drug-induced neutropenia

How to classify neutropenia & why severe cases are medical emergencies

High-risk infections in neutropenic patients

Lymphopenia: causes and clinical significance

🌟 A concise, high-yield walkthrough of every major disturbance in white blood cell counts — packed with mechanisms, mnemonics, case scenarios, and clinically important differentiations designed to boost your diagnostic confidence.

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