For over a century, inbred mice have been at the heart of genetics research. They are undoubtedly one of the most important models in all of biology. But are the mice from inbred lines really as genetically identical as often assumed? Find out in this episode as we hear from Dr Jobran Chebib and Prof. Peter Keightley (University of Edinburgh).
Associated article: Inbred lab mice are not isogenic: genetic variation within inbred strains used to infer the mutation rate per nucleotide site - https://www.nature.com/articles/s41437-020-00361-1