Evidence suggests that THC and CBD each act on specific receptors in the brain to cause different effects on Biomarkers, other neurotransmitter systems and molecular pathways. In fact, CBD can even prevent many of the side effects associated with potent cannabis (high THC cannabis) such as psychosis, paranoia, and in some cases can act as a treatment for those diagnosed with schizophrenia. In this episode of First-Person Science, PhD Candidate & Vanier Scholar Roger Hudson speaks about his recently published manuscript in the Journal Of Neuroscience, discussing how THC causes adverse psychiatric side-effects in some users, and the science of how cannabidiol (CBD) can counteract these side effects. "Cannabidiol (CBD) Counteracts the Psychotropic Side-Effects of Delta-9-Tetrahydrocannabinol (THC) in the Ventral Hippocampus through Bidirectional Control of ERK1–2 Phosphorylation", published in The Journal of Neuroscience [2019 Oct;39(44):8762–8777] / DOI:10.1523/JNEUROSCI.0708-19.2019. https://www.ncbi.nlm.nih.gov/pubmed/31570536