Think Better, Feel Better

Histamine: The Leaky Gut, Leaky Brain Connection


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Although histamine is most often associated with allergies and immune responses, it plays a much more multifaceted role in the body as a hormone, neurotransmitter, and immune system mediator. 


In this episode, Bec is joined by chronic disease expert naturopath, Elizma Lambert to discuss the fascinating topics of mast cell activation syndrome, histamine, and their role in a leaky gut and leaky brain. 


Tune in to learn about the connections between mast cell stabilisation, gut health, and neurotransmitter regulation and explore the interplay between histamine, and glutamate, and how they influence the way you think and feel.


Key Takeaways:


  • Histamine acts as a multifunctional compound in the body, playing roles in neurotransmission, immune response, and hormonal regulation.
  • Mast cell activation syndrome can result from dysregulated mast cells that release excessive histamine, leading to chronic inflammatory responses.
  • Histamine's impact on the brain can contribute to neurological symptoms like anxiety, insomnia, and brain fog.
  • Understanding the interplay between histamine, glutamate, and other neurotransmitters is crucial in addressing histamine-related issues.
  • What are the natural support options for mast cell stabilisation, gut histamine, glutamate and mood? 


Covered in this episode:


[00:00] Welcoming Elizma Lambert

[01:53] Histamine's Multifaceted Role in Health and Disease

[11:49] Post Viral Fatigue and Long-Covid Symptoms

[13:16] Understanding Histamine's Role in Immune Response and Mast Cell Activation

[17:38] Histamine Pathways and Their Impact on Gut and Systemic Health

[26:04] Testing and Identifying Histamine Issues and Mast Cell Activation

[31:41] Histamine's Impact on Brain Receptors and Neurotransmitter Balance

[39:25] The Evolution of Information Access and AI in Healthcare

]42:05] Managing Histamine Issues Through Gut Health and Nutrient Support



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Think Better, Feel BetterBy myBrainCo.