PaperPlayer biorxiv biochemistry

Homology Initialization for Protein Structure Determination via Distance Geometry


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Link to bioRxiv paper:
http://biorxiv.org/cgi/content/short/2020.10.14.339903v1?rss=1
Authors: Tasissa, A., Lai, R., Wang, C.
Abstract:
The problem of finding the configuration of points given partial information on pairwise inter-point distances, the Euclidean distance geometry problem, appears in multiple applications. In this paper, we propose an approach that integrates homology modeling and a nonconvex distance geometry algorithm for the protein structure determination problem. Preliminary numerical experiments show promising results.
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