The courier carrying the book of Revelation from John on Patmos followed a circular route through the seven churches—starting in Ephesus, then Smyrna, Pergamum, Thyatira, Sardis, Philadelphia, and finally Laodicea. Laodicea, the last stop, was a wealthy Phrygian city renowned for its banking industry, fine black wool, and medical school, which produced a famous eye ointment.