Most financial markets still run on one-to-one matching when optimization engines could unlock trillions. Kelly Littlepage co-founded OneChronos after exits to major financial institutions, building the fastest-growing US equities market processing $20 billion daily using Nobel Prize-winning combinatorial auction theory. He breaks down why capital markets lagged behind ad markets in auction sophistication, how machine learning solves NP-hard matching problems at Wall Street speed, and why GPU compute markets need combinatorial auctions to handle non-fungible infrastructure across latency zones and chip architectures.

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