Nourished Brain Podcast

How Caffeine Shapes Your Brain — Focus, Fatigue, and Long-Term Brain Health


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Caffeine — it’s the world’s favorite stimulant and a daily ritual for millions. But what does it really do to your brain? In this episode of The Nourished Brain Podcast, we unpack the science behind caffeine’s short- and long-term effects on focus, mood, sleep, and brain health.

Learn how caffeine interacts with adenosine, the molecule that builds sleep pressure, and why older adults metabolize caffeine more slowly, leading to longer-lasting effects. We’ll also explore the latest research showing that moderate coffee and tea intake may lower the risk of Alzheimer’s and depression — but that too much can backfire on mood and sleep.

🔍 You’ll discover:

  • How caffeine really boosts alertness — and why that 3pm cup might keep you up at night

  • The role of genetics, age, and kidney function in how your body clears caffeine

  • What large meta-analyses reveal about coffee and tea’s protective effects on cognitive decline

  • Why caffeine’s effect on mood is bidirectional — and how to find your personal sweet spot

Whether you’re a latte lover or trying to cut back, this episode helps you understand how caffeine impacts your brain — for better and for worse.

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💡 Have a question you’d like me to cover on the podcast? Or interested in joining as a guest? Looking for a speaker for your event, workshop, or conference? Send me a message at ⁠⁠[email protected]⁠⁠.

🌱 Want to explore 1:1 nutrition therapy?Learn more here: ⁠⁠foodandmoodnutritiontherapy.com⁠⁠.

🧠 Stay up to date on the latest nutrition research for brain and mental health. Subscribe to the Brain Food Digest: ⁠⁠brainfooddigest.beehiiv.com⁠⁠.

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Nourished Brain PodcastBy Sarah Thomsen Ferreira

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