Explain It Like I’m 5

How Do Vaccines Work? A Simple Explanation of Your Immune System and Its Superpowers


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Ever wondered how vaccines actually work, or why people say they “train” your immune system?

In this episode of Explain It Like I’m 5, we break down how vaccines protect your body, how your immune system fights viruses and bacteria, and what really happens after you get a shot.

Host Alex explains complex science in plain language, covering:

  • What is a vaccine and how does it work?

  • The role of white blood cells, antibodies, B cells, and T cells

  • What’s in different types of vaccines: mRNA, live attenuated, inactivated, and protein-based

  • What is herd immunity and why it matters

  • Common vaccine myths and the truth behind them

  • How your body builds immunity and remembers past infections

  • It’s like a Marvel movie happening inside your bloodstream—minus the capes, plus a whole lot of science.

    Whether you're curious about how vaccines fight off viruses, what “immune response” really means, or how vaccination helps prevent disease spread, this episode is your easy-to-understand, no-jargon guide.

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    Explain It Like I’m 5By Alex