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In this expert-led educational video, Dr. Kimberly Brown—Professor of Medicine at Wayne State University and Michigan State University and Transplant Hepatologist at Henry Ford Hospital—breaks down the stages of MASH progression, from early steatosis and inflammation to advanced liver fibrosis and cirrhosis. Dr. Brown explains how untreated MASH can lead to serious complications including portal hypertension, hepatic encephalopathy, variceal bleeding, ascites, liver cancer, and ultimately liver transplantation. With MASH now being the leading cause of liver transplant listings in the U.S., this video underscores the urgency of early intervention and long-term disease management. Watch now to understand the natural history of MASH and why proactive treatment is critical in preventing advanced liver disease. Available on both the CLDF and MASH Alliance websites.