Being a central nervous system depressant when combined with other sedative-hypnotics, Rohypnol can have complicated sedative effects. When Rohypno interacts with a depressant like alcohol, it can lead to severe sedation, blackouts, loss of consciousness, and even respiratory depression. There is a risk of coma, overdose, or death if Rohypnol is mixed with other CNS depressants such as club drugs, alcohol and ketamine.

https://recoverypartnernetwork.com/drug/benzodiazepine/rohypnol-addiction-and-abuse