Pain relief medications like acetaminophen and ibuprofen are staples in everyday care—but emerging research suggests they may play a role in antibiotic resistance. This episode reviews recent findings, explores how these common drugs may influence bacterial response to antibiotics, and highlights pharmacist‑specific considerations. You will walk away with practical insights to support informed medication use and strengthen antibiotic stewardship.

HOST
Rachel Maynard, PharmD
GameChangers Podcast Host and Clinical Editor, CEimpact
Lead Editor, Pyrls

Hunter O. Rondeau, PharmD, BCIDP, AAHIVP
Antimicrobial Stewardship Coordinator, SSM Health
Adjunct Clinical Assistant Professor, University of Kansas School of Pharmacy

Rachel Maynard has no relevant financial relationships with ineligible companies to disclose. 

Hunter Rondeau is a consultant for Pyrls, a speaker for ASHP, and was a speaker for ACCP (ended October 2025) and Vituity (ended May 2025). All relevant financial relationships have been mitigated.
 
CPE REDEMPTION
This course is accredited for continuing pharmacy education! Click the link below that applies to you to take the exam and evaluation:

• If you are already enrolled in this course, click here to redeem your credit. 
• To purchase this episode and claim your CPE credit, click here.

CPE INFORMATION
Learning Objectives
Upon successful completion of this knowledge-based activity, participants should be able to:
1. Describe emerging evidence on how common OTC pain medications may influence antibiotic resistance.
2. Identify pharmacist strategies to optimize analgesic and antibiotic use while supporting antimicrobial stewardship.

0.05 CEU/0.5 Hr
UAN: 0107-0000-25-372-H01-P
Initial release date: 12/8/2025
Expiration date: 12/8/2026
Additional CPE details can be found here.

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