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How Safe Are Psychedelics? Sorting Facts From Myths With Deanna Kaplan
Welcome to another episode of Webdelics, the podcast where we peel back the layers of myth and misinformation to explore the real science—and the mysteries—behind psychedelics and plant medicines. In this episode, host Scott Mason sits down with Dr. Deanna Kaplan, a clinical psychologist and assistant professor at Emory University School of Medicine, for a fascinating conversation about the cutting-edge research into psychedelics like psilocybin and MDMA.
Together, they dive into why the science around these substances is still so new and what it means for anyone considering a psychedelic journey today. Dr. Kaplan explains how decades of legal restrictions have left us with a scientific field in its infancy, why most current studies are small and limited, and what we do—and don’t—know about the safety and risks involved.
They also tackle big questions about consciousness, the metaphysical experiences reported on psychedelics, and whether traditional scientific methods can truly capture the transformative, symbolic nature of these journeys. Plus, they discuss where the field is headed, the importance of building a broader scientific knowledge base, and what makes psychedelics unique compared to other medicines.
Get ready for an honest, wide-ranging conversation that’s equal parts science, philosophy, and personal insight. Whether you’re curious about the latest research, considering your own psychedelic experience, or just hungry for a deeper understanding of the psychedelic renaissance, this episode is packed with thought-provoking ideas that will stay with you long after you listen.
00:00 – Introduction
04:11 – The Emerging Science of Psychedelics and Historical Context
08:41 – Millennia of Use vs. Modern Scientific Study
11:19 – Psychedelics and Mental Health Treatment in 2024
16:09 – Understanding Bad Trips: Distress and Meaning
19:34 – Personal Story: Overcoming Fear During a Psilocybin Journey
20:49 – Lessons on Fear: Control, Temporariness, and Health Considerations
26:50 – SSRIs vs. Psychedelics: Comparing Effects on Mood and Perception
27:50 – Psychedelics and the Challenge to Modern Psychiatry
34:04 – The Need for Research on Psilocybin Therapy for Non-Intense Experiences
35:16 – PTSD Treatment: Different Patient Preferences and Approaches
38:32 – Acting Despite Incomplete Scientific Evidence
43:41 – Psilocybin Clinical Trials and Future Integration into Healthcare
46:53 – Conclusion: Webdelics Community and Future Topics
View all episodes
By Mark McNally, Chiara Burns, Scott MasonWelcome to another episode of Webdelics, the podcast where we peel back the layers of myth and misinformation to explore the real science—and the mysteries—behind psychedelics and plant medicines. In this episode, host Scott Mason sits down with Dr. Deanna Kaplan, a clinical psychologist and assistant professor at Emory University School of Medicine, for a fascinating conversation about the cutting-edge research into psychedelics like psilocybin and MDMA.
Together, they dive into why the science around these substances is still so new and what it means for anyone considering a psychedelic journey today. Dr. Kaplan explains how decades of legal restrictions have left us with a scientific field in its infancy, why most current studies are small and limited, and what we do—and don’t—know about the safety and risks involved.
They also tackle big questions about consciousness, the metaphysical experiences reported on psychedelics, and whether traditional scientific methods can truly capture the transformative, symbolic nature of these journeys. Plus, they discuss where the field is headed, the importance of building a broader scientific knowledge base, and what makes psychedelics unique compared to other medicines.
Get ready for an honest, wide-ranging conversation that’s equal parts science, philosophy, and personal insight. Whether you’re curious about the latest research, considering your own psychedelic experience, or just hungry for a deeper understanding of the psychedelic renaissance, this episode is packed with thought-provoking ideas that will stay with you long after you listen.
00:00 – Introduction
04:11 – The Emerging Science of Psychedelics and Historical Context
08:41 – Millennia of Use vs. Modern Scientific Study
11:19 – Psychedelics and Mental Health Treatment in 2024
16:09 – Understanding Bad Trips: Distress and Meaning
19:34 – Personal Story: Overcoming Fear During a Psilocybin Journey
20:49 – Lessons on Fear: Control, Temporariness, and Health Considerations
26:50 – SSRIs vs. Psychedelics: Comparing Effects on Mood and Perception
27:50 – Psychedelics and the Challenge to Modern Psychiatry
34:04 – The Need for Research on Psilocybin Therapy for Non-Intense Experiences
35:16 – PTSD Treatment: Different Patient Preferences and Approaches
38:32 – Acting Despite Incomplete Scientific Evidence
43:41 – Psilocybin Clinical Trials and Future Integration into Healthcare
46:53 – Conclusion: Webdelics Community and Future Topics